Cup of tea?
Many of us have great faith in the soothing and restoring powers
of a nice cup of tea, but could the health benefits of our favourite
tipple go even further? As part of a massive international research
effort underway to try and understand more about tea, scientists
at the Institute of Food Research on the Norwich Research Park have
made their own contribution to increasing our knowledge about this
age-old drink.
For centuries, tea has been a cultural cornerstone of meals and
celebrations for people in many Asian countries. And serving high
quality (and sometimes very expensive!) green tea to your guests
is still a symbol of status in China - a far cry from our less traditional
habit of dunking a tea bag in a mug of hot water.
But tea, and green tea in particular, is attracting the interest
of scientists all over the world, as it seems to contain chemicals
that help protect us against certain diseases. So researchers are
trying to find out just what these chemicals are, and how they might
help keep us healthy by combating the harmful things in our bodies.
Some of the "bad guys" that cause problems in our bodies
are free radicals; particularly dangerous are those formed spontaneously
from reactions involving oxygen. As we breathe oxygen to live, we
also generate lots of these highly reactive harmful by-products
(free radicals) at the same time. Heart disease, ageing and cancer
have all been attributed to the action of free radicals, so finding
ways of "mopping them up" is thought to be one solution
to staying healthy for longer.
Although our bodies have inbuilt mechanisms to mop up free radicals,
several foods contain chemicals, such as Vitamin E, that make this
process more effective. And tea, particularly the green type, contains
related chemicals known as polyphenols, which also help to destroy
free radicals. The challenge is to identify these polyphenols and
see how they work.
The Institute of Food Research is one of the world centres for
analysing the health-giving components of food. The expertise in
free radical chemistry at IFR attracted a group from a Chinese laboratory
who were working on green tea, and several of their scientists have
been to IFR to work alongside the Norwich scientists.
Armed with a traditional tea variety, one of their scientists worked
at IFR for more than a year. During that time she studied the way
that free radicals are mopped up by the polyphenols in a particular
variety of green tea.
In an attempt to provide conditions similar to those in the cells
of our body, the scientists made tiny "spheres" out of
synthetic cell membranes. To these spheres, they added some well-studied
free radicals, then mixed them with the tea. The scientists were
then able to detect whether the free radicals in the spheres had
been destroyed by the polyphenols in the tea.
There are four major polyphenols in green tea that destroy free
radicals. Some of the polyphenols are more effective than others,
but all seem to have a role to play in the health-giving properties
of the tea.
Sadly the funding for this project has finished but the work is
continuing in China. The contribution made by IFR scientists in
the collaboration with the Chinese group has hopefully put one more
piece in the massive jigsaw that is our understanding of protective
foods.
© Dr Belinda Clarke 2003
This Article originally appeared as part of the "Science
on your Doorstep" series, published in the Eastern Daily Press
12th April 2003

NRP
Partners
Partners of the Norwich
Research Park include the John Innes Centre (JIC), the Institute
of Food Research (IFR), the University of East Anglia (UEA), the
Sainsbury Laboratory (SL) and the Norfolk and Norwich University
Hospital (N&NUH).
Web addresses of the NRP partners
www.jic.bbsrc.ac.uk
www.ifr.bbsrc.ac.uk
www.uea.ac.uk
www.nnuh.nhs.uk
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